body{margin:0}
.lw-page{container-type:inline-size;--d:'Fraunces',Georgia,'Times New Roman',serif}
.lw-page a{color:#3F5B45;text-decoration-thickness:2px;text-underline-offset:4px}
.lw-page a:hover{color:#2C4332;text-decoration-thickness:3px}
.lw-page a:focus-visible,.lw-page summary:focus-visible,.lw-page button:focus-visible{outline:3px solid #27302A;outline-offset:3px;box-shadow:0 0 0 3px #E3C58C}
.lw-wrap{max-width:1280px;margin:0 auto;box-sizing:border-box;padding-inline:20px;padding-inline:clamp(20px,5cqi,48px)}
.lw-top{background:#EEF0E4;padding-block:28px;padding-block:clamp(28px,3cqi,44px)}
.lw-kicker{margin:0 0 12px;font-size:18px;font-weight:700;color:#3F5B45}
.lw-top h1{margin:0;max-width:22em;font:600 34px/1.1 var(--d);font:600 clamp(34px,4.6cqi,52px)/1.1 var(--d);letter-spacing:-0.02em;text-wrap:balance}
.lw-subnav{list-style:none;margin:20px 0 0;padding:0;display:flex;flex-wrap:wrap;gap:8px 12px}
.lw-page .lw-pill{display:inline-flex;align-items:center;min-height:48px;box-sizing:border-box;padding:0 20px;border:2px solid #3F5B45;border-radius:999px;background:#fff;font-size:18px;font-weight:700;text-decoration:none}
.lw-page .lw-pill:hover{background:#F7F5EE}
.lw-page .lw-pill[aria-current="page"],.lw-page .lw-pill[aria-current="page"]:hover{background:#3F5B45;color:#fff}
.lw-prose{padding-block:24px 40px;padding-block:clamp(24px,2.5cqi,32px) clamp(40px,4cqi,56px)}
.lw-prose>*{max-width:840px}
.lw-prose>.lw-wide{max-width:none}
.lw-prose h2{margin:56px 0 12px;font:600 27px/1.2 var(--d);font:600 clamp(27px,3cqi,34px)/1.2 var(--d);letter-spacing:-0.01em;text-wrap:balance}
.lw-prose h3{margin:40px 0 8px;font:600 22px/1.25 var(--d);font:600 clamp(22px,2.3cqi,26px)/1.25 var(--d)}
.lw-prose p{margin:14px 0}
.lw-prose ul,.lw-prose ol{margin:14px 0;padding-left:1.4em}
.lw-prose li{margin:10px 0}
.lw-prose li::marker{color:#3F5B45;font-weight:700}
.lw-c{font-weight:600;white-space:nowrap}
.lw-prose .lw-glance{margin:0 0 24px;padding:20px 24px;border-radius:20px;background:#F7F5EE}
.lw-glance b:first-child,.lw-label{display:block;margin-bottom:4px;font-size:18px;font-weight:700;color:#3F5B45}
.lw-prose .lw-soon{margin:24px 0;padding:20px 24px;border-radius:20px;background:#F7F5EE;color:#27302A}
.lw-soon b{display:block;margin-bottom:4px;font-size:18px;font-weight:700;color:#3F5B45}
.lw-prose .lw-next{margin:48px 0 0}
.lw-page .lw-btn{display:inline-flex;align-items:center;justify-content:center;min-height:60px;box-sizing:border-box;padding:14px 32px;border:2px solid #B96F4C;border-radius:999px;background:#D98E6A;color:#27302A;font:600 20px/1.25 var(--d);text-align:center;text-decoration:none;cursor:pointer}
.lw-page .lw-btn:hover{background:#E3C58C;color:#27302A}
.lw-toc{margin:0 0 8px;padding:20px 24px;border:1px solid #E2E0D2;border-radius:20px;background:#fff}
.lw-toc ul{list-style:none;margin:4px 0 0;padding:0;display:grid;grid-template-columns:repeat(auto-fit,minmax(min(240px,100%),1fr));gap:0 24px}
.lw-prose .lw-toc li{margin:0}
.lw-toc a{display:inline-flex;align-items:center;min-height:44px}
.lw-tw{position:relative;margin:20px 0;overflow-x:auto;border:1px solid #E2E0D2;border-radius:20px;background:#fff}
.lw-tw table{width:100%;border-collapse:collapse;font-size:18px;line-height:1.45}
.lw-tw th{padding:14px 16px;background:#3F5B45;color:#fff;text-align:left;font-weight:700;vertical-align:bottom}
.lw-tw td{padding:14px 16px;border-top:1px solid #E2E0D2;vertical-align:top}
@container (max-width:759px){
.lw-tw thead{position:absolute;width:1px;height:1px;overflow:hidden;clip-path:inset(50%)}
.lw-tw tr{display:block;padding:14px 16px;border-top:1px solid #E2E0D2}
.lw-tw tbody tr:first-child{border-top:0}
.lw-tw td{display:block;padding:3px 0;border:0}
.lw-tw td:first-child{font-weight:700}
.lw-tw td[data-th]::before{content:attr(data-th) ": ";font-weight:700;color:#56605A}
}
@media (prefers-reduced-motion:reduce){.lw-page *{transition:none !important;animation:none !important;scroll-behavior:auto !important}}
/* ---- buttons ---- */
.lw-page .lw-btn{border-color:#3F5B45;background:#3F5B45;color:#fff;font-family:inherit;font-weight:700}
.lw-page .lw-btn:hover{border-color:#2C4332;background:#2C4332;color:#fff}
.lw-page .lw-btn2{border-color:#3F5B45;background:#fff;color:#3F5B45}
.lw-page .lw-btn2:hover{border-color:#2C4332;background:#F7F5EE;color:#2C4332}

/* ---- variants page ---- */
.lw-prose .lw-note{color:#56605A}
.lw-prose .lw-panel{margin:24px 0;padding:20px 24px;border-radius:20px;background:#F7F5EE}
.lw-prose .lw-panel>:first-child{margin-top:0}
.lw-prose .lw-panel>:last-child{margin-bottom:0}
.lw-prose .lw-panel h3{margin-top:0}
.lw-prose .lw-panel.lw-sage{background:#EEF0E4}
.lw-cls{display:inline-block;padding:2px 12px;border-radius:14px;font-size:18px;font-weight:700;line-height:1.4;white-space:normal}
.lw-cls-p{background:#DCE7DD;color:#2C4332}
.lw-cls-u{background:#F4E6C8;color:#4A3A16}
.lw-cls-c{background:#F1DCD0;color:#5A3020}
.lw-cls-b{background:#E7E9E2;color:#27302A}
.lw-tw .lw-sub{display:block;color:#56605A}
.lw-tw .lw-mine td{background:#F2F5EC}
.lw-scale{list-style:none;padding:0;margin:20px 0;display:grid;grid-template-columns:repeat(auto-fit,minmax(min(140px,100%),1fr));gap:8px}
.lw-prose .lw-scale li{margin:0;padding:12px 16px;border-radius:16px;background:#EEF0E4}
.lw-prose .lw-scale li.is-vus{background:#F4E6C8}
.lw-scale b{display:block;font-family:var(--d);font-weight:600;font-size:20px}
.lw-prose .lw-code{font-family:ui-monospace,'SFMono-Regular',Menlo,Consolas,monospace;font-size:18px;overflow-wrap:anywhere}
.lw-prose dl.lw-parts{margin:14px 0}
.lw-prose dl.lw-parts dt{font-weight:700;margin-top:12px}
.lw-prose dl.lw-parts dd{margin:2px 0 0}
.lw-stars{white-space:nowrap}
@container (max-width:759px){
.lw-tw .lw-mine{background:#F2F5EC}
.lw-tw .lw-mine td{background:transparent}
}
/* ---- visual review fixes ---- */
/* points scale: tiles line up with the text; on phones it reads as a ladder, one row per class */
.lw-prose .lw-scale{padding:0}
.lw-prose .lw-scale li{overflow-wrap:break-word;hyphens:auto}
@container (max-width:560px){
.lw-scale{grid-template-columns:1fr}
.lw-prose .lw-scale li{display:grid;grid-template-columns:7.5em minmax(0,1fr);gap:12px;align-items:baseline;padding:10px 16px}
}
/* ClinVar column: the classification on its own line, stars and record number kept together */
.lw-tw td[data-th="ClinVar"]{min-width:11em}
.lw-tw td[data-th="ClinVar"] .lw-cls{display:block;width:fit-content;max-width:100%;box-sizing:border-box;margin:0 0 6px}
.lw-tw td[data-th="ClinVar"] a{white-space:nowrap}
@container (max-width:380px){.lw-prose .lw-scale li{display:block}}